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ID-MAGIC: Individualised Dose optiMisAtion of Ganciclovir in Immunocompromised Children Trial

This is a multicentre, pragmatic, adaptive, two-arm, open label randomised control trial at seven major paediatric hospitals in Australia and New Zealand aims to determine in immunocompromised children with cytomegalovirus viraemia whether individualised intravenous ganciclovir dosing using a web app is superior to standard intravenous ganciclovir dosing in achieving virological clearance. 

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Advancing the evidence base for off-label medications in children
  • Projects
  • BEST Trial: Bone and Joint infection – Simplifying treatment in Children Trial
  • FosUTI Trial: Optimising the treatment of antibiotic resistant urinary tract infections in children
  • O-SNAP: Optimizing antibiotic dosing in the Staphylococcus aureus Network Adaptive Platform trial
  • ID-MAGIC: Individualised Dose optiMisAtion of Ganciclovir in Immunocompromised Children Trial
  • Advancing the evidence base for off-label medications in children
  • Audit of therapeutic drug monitoring of Vancomycin in paediatric tertiary hospitals
  • A pharmacokinetic study of fluoroquinolones using capillary microsampling
  • Future directions – scoping literature review for antimicrobials for drug-resistant bacterial infections in children
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